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Pueraria Clear Sinus

 

CLINICAL APPLICATIONS

* Sinusitis or rhinitis with purulent, yellow nasal discharge

* Sinus infection with headache, pain, and nasal obstruction

* General nasal problems including stuffy nose, sneezing, loss of smell, and yellow sticky nasal discharge

 

WESTERN THERAPEUTIC ACTIONS

* Antiallergic and antihistamine effects to treat allergy-induced sinusitis or rhinitis

* Antibiotic (antibacterial and antiviral) activities to treat bacterial and viral infections of the nose and the sinus cavity

* Anti-inflammatory effect to constricts the vessels in the nasal mucosa to open up sinus passages

* Analgesic effect to relieve sinus headache and pain

 

CHINESE THERAPEUTIC ACTIONS

* Dispels damp-heat accumulation

* Removes fluid congestion

* Unblocks nasal obstruction

* Clears heat and dispels purulent infection

* Alleviates sinus pain

 

DOSAGE

For treatment of sinusitis, rhinitis or sinus infection, take 4 to 6 capsules three times daily with warm water on an empty stomach one hour before or two hours after meals. For maintenance or prevention, take 3 capsules two times daily.

 

INGREDIENTS


Bai Shao (Radix Paeoniae Alba)

Bai Zhi (Radix Angelicae Dahuricae)

Cang Er Zi (Fructus Xanthii), dry fried

Chuan Xiong (Rhizoma Chuanxiong)

Da Huang (Radix et Rhizoma Rhei)

Da Zao (Fructus Jujubae)

Gan Cao (Radix et Rhizoma Glycyrrhizae)

Ge Gen (Radix Puerariae Lobatae)

Gui Zhi (Ramulus Cinnamomi)

Huang Qin (Radix Scutellariae)

Jie Geng (Radix Platycodonis)

Sheng Jiang (Rhizoma Zingiberis Recens)

Shi Gao (Gypsum Fibrosum)

Xin Yi Hua (Flos Magnoliae)


 

BACKGROUND

Sinusitis and rhinitis are common disorders of the nose. Sinusitis is the inflammation of the paranasal sinuses with symptoms such as nasal obstruction and congestion, purulent rhinorrhea, pain, fatigue and fever. Sinusitis may be caused by viral, bacterial or fungal infection. Rhinitis is inflammation of the nasal mucous membrane with symptoms such as nasal congestion, rhinorrhea, itching and sneezing. Rhinitis is usually caused by allergy, irritation, and viral infection.

 

FORMULA EXPLANATION

Pueraria Clear Sinus is formulated to treat sinusitis, rhinitis or sinus infection due to damp-heat and fluid congestion. Clinically, common signs and symptoms include stuffy nose, sticky yellow discharge, loss of ability to smell, and sinus headache.

        Xin Yi Hua (Flos Magnoliae) and Cang Er Zi (Fructus Xanthii) are the chief herbs in this formula. They have acrid, dispersing, and decongestant properties to unblock the nasal passages. Huang Qin (Radix Scutellariae), Shi Gao (Gypsum Fibrosum) and Da Huang (Radix et Rhizoma Rhei) clear heat, reduce inflammation and neutralize the warming properties of the chief herbs. Gui Zhi (Ramulus Cinnamomi) and Bai Shao (Radix Paeoniae Alba) harmonize the wei (defense) and ying (nutritive) levels to dispel external pathogenic influences. Ge Gen (Radix Puerariae Lobatae) dispels wind-heat and alleviates pain. Chuan Xiong (Rhizoma Chuanxiong) relieves sinus headache. Jie Geng (Radix Platycodonis) and Bai Zhi (Radix Angelicae Dahuricae) eliminate pus and resolve nasal discharge and post-nasal drip associated with sinus infection. Da Zao (Fructus Jujubae), Sheng Jiang (Rhizoma Zingiberis Recens), and Gan Cao (Radix et Rhizoma Glycyrrhizae) harmonize the formula and protect the middle jiao.

        In short, Pueraria Clear Sinus clears damp-heat from the nose to treat sinusitis, rhinitis or sinus infection.

 

CAUTIONS & CONTRAINDICATIONS

* This formula is contraindicated during pregnancy and nursing.

* This formula is designed for sinusitis or rhinitis due to damp-heat with yellow and sticky discharge. Sinusitis or rhinitis due to wind-cold with clear watery discharge should be treated with Magnolia Clear Sinus.

* Cang Er Zi (Fructus Xanthii) used in this formula has been carefully dry fried at high temperature until they appear dark brown or slightly charred, as dictated by Chinese Materia Medica. Dry frying is necessary because this process simultaneously increase the effect [by enhancing the extraction of active compounds] and decreases the side effects [by destroying the undesired glycosides]. Nonetheless, because Cang Er Zi (Fructus Xanthii) is metabolized by the liver and eliminated by the kidney, individuals with pre-exiting liver or kidney diseases should not take this formula.[1]

* The following warning statement is required by the State of California: “This product contains Da Huang (Radix et Rhizoma Rhei). Read and follow directions carefully. Do not use if you have or develop diarrhea, loose stools, or abdominal pain because Da Huang (Radix et Rhizoma Rhei) may worsen these conditions and be harmful to your health. Consult your physician if you have frequent diarrhea or if you are pregnant, nursing, taking medication, or have a medical condition.”

 

CLINICAL NOTES

* Approximately 25% of all sinusitis are related to food allergies. Therefore, it is extremely important to identify and avoid the allergen. Common allergens include milk, wheat, eggs, citrus fruits, corn and peanuts.

* Some patients may experience mild stomach discomfort while taking this herbal formula. If such a reaction occurs, ask the patient to reduce the dosage and increase the frequency of administration (instead of taking 4 capsules three times daily, take 2 capsules six times a day). Taking the herbs with food may prevent stomach discomfort.

* Pueraria Clear Sinus is more effective for sinus infections. Magnolia Clear Sinus is more effective for sinusitis and rhinitis due to seasonal allergies.

 

Pulse Diagnosis by Dr. Jimmy Wei-Yen Chang:

* Superficial and forceful pulse on the right cun.

 

SUPPLEMENTARY FORMULAS

* For infection of the ear, nose, and throat, add Herbal ENT.

* To enhance the overall antibacterial function, add Herbal ABX.

* To enhance the overall antiviral function, add Herbal AVR.

* For profuse yellow phlegm, post-nasal drip, dyspnea, or chest congestion, use Pinellia XPT.

* With more underlying damp and phlegm with Spleen qi deficiency, add Pinellia Complex.

* For wind-heat at the exterior, add Lonicera Complex.

* For Lung heat with cough, dyspnea, and fever, add Respitrol (Heat).

* For acute headache, add Corydalin (AC).

* For chronic headache due to deficiency, add Corydalin (CR).

* For nasal symptoms associated with environmental or toxic poisoning, add Herbal DTX.

* For excess heat, add Gardenia Complex.

* To strengthen the constitution of the body, use Imperial Tonic.

* To enhance immunity against allergies, take Immune + at a low dose (1 to 2 capsules a day) during non-allergy seasons.

* With severe inflammation, combine with Astringent Complex.

 

ACUPUNCTURE TREATMENT

Traditional Points:

* Feishu (BL 13), Hegu (LI 4), Quchi (LI 11), Shangyang (LI 1), Lingtai (GV 10)

* Shaoshang (LU 11), Quchi (LI 11), Yingxiang (LI 20)

 

Classic Master Tung's Points:

* Allergy: Mu (T 11.17), Linggu (T 22.05), Tianshi (T 33.15), Dishi (T 33.14), Renshi (T 33.13), Simashang (T 88.18), Simazhong (T 88.17), Simaxia (T 88.19), Yingxiang (LI 20), Tongtian (T 88.03), Tongguan (T 88.01), Zhenjing (T 1010.08), Shangli (T 1010.09), Shuitong (T 1010.19), Shuijin (T 1010.20), Fenjin (T 44.01), Zhengben (T 1010.12). Bleed dark veins nearby Sihuawai (T 77.14). Bleed before needling for best result.

* Nose (stuffy): Linggu (T 22.05), Jianzhong (T 44.06), Mu (T 11.17), Tianshi (T 33.15), Dishi (T 33.14), Renshi (T 33.13), Zhenjing (T 1010.08), Simashang (T 88.18), Simazhong (T 88.17), Simaxia (T 88.19)

* Absence of smell: Fukuai (T 1010.15), Liukuai (T 1010.16), Simashang (T 88.18), Simazhong (T 88.17), Simaxia (T 88.19). Bleed dark veins nearby Sihuashang (T 77.08), Sihuazhong (T 77.09), Sihuaxia (T 77.11) and Weizhong (BL 40). Bleed before needling for best result.

 

Master Tung’s Points by Dr. Chuan-Min Wang:

* Allergy, sinusitis, rhinitis: Needle Lianquan (CV 23) using the Remove Dust 7 needling technique (from Ling Shu). Needle bilaterally Tianrong (SI 17), Fenjin (T 44.01), Sanyinjiao (SP 6).

 

Balance Method by Dr. Richard Tan:

* Left side: Chize (LU 5), Taiyuan (LU 9), Zusanli (ST 36), Xiangu (ST 43)

* Right side: Sanjian (LI 3), Quchi (LI 11), Taibai (SP 3), Yinlingquan (SP 9)

* Left and right sides can be alternated from treatment to treatment.

 

Auricular Medicine by Dr. Li-Chun Huang:

* Stuffy nose: Lung, Internal Nose, Adrenal Gland, External Ear, Nasopharynx. Bleed Ear Apex.

* Allergies: Allergic Area, Endocrine, Adrenal Gland, Spleen. Bleed Ear Apex.

* Chronic rhinitis: Internal Nose, External Ear, Lower Lung, Allergic Area, Adrenal Gland

* Allergic rhinitis: Internal Nose, External Ear, Adrenal Gland, Endocrine, Allergic Area, Spleen, Lung, Sympathetic. Bleed Ear Apex.

* Sinusitis: Upper Jaw, Upper Palate, Forehead, Internal Nose, External Ear, San Jiao, Lung, Endocrine, Adrenal Gland, corresponding points

* Nasopharyngitis, post nasal drip: Nasopharynx, Sympathetic, Allergic Area, Lung, Endocrine, Trachea. Bleed Ear Apex.

* Snoring, apnea: Trachea, San Jiao, Lower Lung, Pharynx, Larynx, Sympathetic, Nasopharynx, Chest, Mouth, Esophagus, Tooth

 

NUTRITION

* Reduce or eliminate the intake of dairy products, as they increase mucus production.

* Drink plenty of distilled water throughout the day to help drainage.

* Make sure the diet contains an adequate amount of vitamin A and C. Vitamin A is essential for healthy mucous lining of the respiratory tract. Vitamin C is well recognized for its effect to prevent and treat infection.

* The Spleen is responsible for generating post-natal qi and good Spleen function also contributes to a healthy immune system. Foods that damage the Spleen should be avoided:

§ Avoid any and all foods that contain sugar, such as cake, dessert, candy, chocolate, canned juice, soft drinks, caffeinated drinks, stevia, sugar substitutes, agave, xylitol, and corn syrup.

§ Avoid raw or uncooked meats, such as sashimi, sushi, steak tartar, and seared meat. Minimize consumption of foods that are cooling in nature, including tofu, tomato, celery, asparagus, bamboo, seaweed, kelp, bitter melon, cucumber, gourd, luffa, eggplant, winter melon, watermelon, honeydew, citrus, oranges, guava, grapefruit, pineapple, plums, pear, banana, papaya, white radish, mustard leaf, potherb mustard, Chinese kale, napa, and bamboo sprout. Do not eat foods straight from the refrigerator. Long-term intake of cold fruits and vegetables like the ones listed above may be damaging to the Spleen. The cooling property of foods can be neutralized by cooking or adding 20 pieces of Gou Qi Zi (Fructus Lycii).

§ Avoid carbohydrates like white rice or bread as they may produce dampness.

§ No seafood especially shellfish, like crabs, oyster, scallops, clams, lobster and shrimp (they enter the yangming Stomach channel).

§ Avoid fermented foods like cheese or fermented tofu.

§ Do not eat dairy products, such as milk, cream, yogurt, cheese, and ice cream.

§ No lamb, beef, goose or duck.

§ Avoid fried or greasy foods.

* Warm and hot natured foods that damage qi and yin should be avoided, such as:

§ certain fruits like mango and durian that produce heat.

§ stimulants like coffee, alcohol, and energy drinks.

§ spicy/pungent/aromatic vegetables such as pepper, garlic, onions, basil, rosemary, cumin, funnel, anise, leeks, chives, scallions, thyme, saffron, wormwood, mustard, chili pepper, and wasabi.

* Avoid food and drinks with artificial coloring.

* Consume as few meat products as possible. Do not eat processed meats, such as lunch meats, hot dogs and sausages, as they contain nitrites that are associated with inflammation and chronic disease.

 

The Tao of Nutrition by Dr. Maoshing Ni and Cathy McNease:

* Allergy

§ Recommendations: ginger, onions, garlic, bamboo shoots, cabbage beets, beet top tea, carrots, leafy greens, yams, and ganoderma mushroom.

§ Drink ginger tea to induce sweating.

§ Drink beet top tea as a water source.

§ Avoid wheat, citrus fruits, chocolate, shellfish, dairy products, eggs, potatoes, polluted meats, and polluted air.

* Chronic sinusitis

§ Recommendations: ginger, green onions, magnolia flower, bananas, garlic, black mushrooms, chrysanthemum flowers, mulberry leaves, and apricot kernel.

§ Make tea from magnolia flower, basil, ginger, and green onion. Drink three times daily for at least one week.

§ Combine magnolia flowers and eggs, cook and eat.

§ Make tea from mulberry leaves and chrysanthemums, then cook rice porridge in the tea, adding apricot kernels.

§ Boil tea of mint, basil, and ginger. While boiling the tea, inhale the steam through the nose, three times daily for at least two months.

§ Avoid coffee and stop smoking.

 

LIFESTYLE INSTRUCTIONS

* Avoid allergens that may trigger sinusitis and rhinitis.

* Application of saline solution to the nose three to four times daily helps to reduce nasal congestion.

* Strengthen the immune system by increasing exercise, reducing worry and stress, and developing a normal sleep pattern.

* Steam inhalation is helpful to drain sinus infections. Rinsing the nostrils with cold saline water is helpful to desensitize the nose to temperature and common allergens. Repeatedly suck in and blow out the cold saline water for one to two minutes every morning.

 

CASE STUDIES

* M.B., a 37-year-old male, presented with pain located on the forehead that had been occurring for three days. Additional symptoms included thick yellow mucus and a fever of 102°F. Pain was also found upon palpation of his sinal cavities. His Western diagnosis was sinusitis and the TCM diagnosis was wind-heat. Upon the diagnosis, the patient was administered Pueraria Clear Sinus and Herbal ABX, both at four capsules three times a day. In one day the fever had cleared, followed by decreased in pain in two days. The sinuses finally resolved within a week. Submitted by A.I., Hilo, Hawaii.

* L.T., a 28-year-old male, presented with allergies, sneezing, occipital stiffness, and sinus headache along the Stomach and Gallbladder channels. Clear copious phlegm was also present. Pulse was wiry and big on the left side and slippery and big on the right side. The practitioner diagnosed this condition as wind-cold allergies with phlegm dampness. The patient was given Pueraria Clear Sinus at four capsules three times a day. With Pueraria Clear Sinus the allergies resolved within 1 week of taking the formula. He continues to take it whenever he experiences an allergic reaction. Submitted by L.M., Lafayette, Colorado.

* M.C., a 60-year-old male, presented with cough and nasal congestion with yellow discharge. He had been previously diagnosed with sinusitis and bronchitis and was currently taking antibiotics. There had been a chronic case of allergies triggering repeated episodes of his sinus infections and bronchitis. The patient would get an episode every 2 to 3 months and had been on a lot of antihistamine and cortisone medications. The practitioner diagnosed this condition as exterior wind-heat with phlegm heat. Upon diagnosis, the patient was prescribed Pueraria Clear Sinus and Herbal ABX. With taking the herbs, the patient reported her sinusitis and bronchitis had cleared, the discharge lessened in amount and the color became clear. Submitted by B.L., Fort Myers, Florida.

* A robustly healthy female presented with flu symptoms. She had a sore throat and yellow mucus. The practitioner diagnosed her condition as wind-heat. In conjunction with acupuncture treatment, the practitioner also had the patient utilize a vaporizer for steaming her face. Lonicera Complex and Pueraria Clear Sinus worked quite effectively after taking them for three to four days at larger dosages. The practitioner also noted that Pu Ji Xiao Du Yin (Universal Benefit Decoction to Eliminate Toxin) could be used if the condition was more severe and had presence of heat and toxins. Submitted by S.C., La Crescenta, California.

* A 28-year-old male presented with dizziness, sinus drainage, ringing in the ears, bitter taste in the mouth, and night sweating for about five weeks. His tongue was dry with a red tip and a greasy yellow coating. His pulse was at 80 beats per minute, fast and superficial with Kidney, Spleen/Stomach deficient. His medical doctor diagnosed his condition to be caused by fluid in the ears. The practitioner diagnosed the condition as nasal obstruction due to heat. A combination herbal treatment of Pueraria Clear Sinus and Zhi Bai Di Huang Wan (Anemarrhena, Phellodendron, and Rehmannia Pills) was administered. Dizziness was resolved within two days of the treatment. The patient noted that the herbal formulas worked much better for his condition than the antihistamines. Submitted by S.T., San Jose, California.

* A 42-year-old midwife presented with sinus infection (for ten days) with yellow green discharge, increased pressure and pain in the sinus cavity and the ears, and severe pain. Upon examination, it was found that there was also lymph node swelling and pain. The TCM diagnosis was phlegm heat in the Lung and toxic heat in the throat. The patient was instructed to take Pueraria Clear Sinus (4 capsules three times daily) and Herbal ABX (4 capsules three times daily). Within one day, the patient responded that there was a lot less pain and marked decrease in swelling. She continued to improve with each dose and stated that she felt “all better” by the third day. The practitioner commented the formulas were “very amazing and powerful.” Submitted by M.N., Knoxville, Tennessee.

* A 33-year-old male presented with frontal headaches with yellow nasal discharge. No body aches or fever were reported. His pulse was rapid. The practitioner diagnosed the condition as phlegm heat and wind-heat. The patient took Pueraria Clear Sinus for ten days (6 capsules three times daily). Subsequently, his phlegm and headaches resolved. Submitted by M.K., Sherman Oaks, California.

 

PHARMACOLOGICAL AND CLINICAL RESEARCH

Pueraria Clear Sinus is formulated to treat sinusitis, rhinitis or sinus infection. The ingredients in this formula have antibiotic (antibacterial, antiviral and antifungal) effects to treat infection, antiallergic and antihistamine effects to treat allergy, and anti-inflammatory effects to reduce swelling and inflammation. Together, they effectively treat both the causes and the symptoms of rhinitis and sinusitis.

        Pueraria Clear Sinus uses many herbs with antibacterial effects to treat the cause of the disease. Huang Qin (Radix Scutellariae) has a wide-spectrum inhibitory effect against Staphylococcus aureus, beta-hemolytic streptococcus, Diplococcus pneumoniae, Pseudomonas aeruginosa, Bacillus dysenteriae, E. coli, Bordetella pertussis, Vibrio cholerae, Diplococcus meningitidis, leptospira and various species of dermatophytes and influenza viruses. Huang Qin (Radix Scutellariae) is most effective against Staphylococcus aureus and Pseudomonas aeruginosa. Furthermore, it was discovered that the effectiveness of standard antibiotics such as ampicillin, amoxicillin, methicillin and cefotaxime can be potentiated with addition of baicalin, a flavone isolated from this herb. With the addition of baicalin, the effectiveness of these beta-lactam antibiotics was restored against beta-lactam-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA).[2],[3] Da Huang (Radix et Rhizoma Rhei) also has a broad-spectrum antibiotic effect. It is most effective against the streptococcus and staphylococcus species of bacteria. It also inhibits the activity of Corynebacterium diphtheriae, Bacillus subtilis, Salmonella typhi, and Bacillus dysenteriae. Constituents responsible for the antibiotic effect include emodin, rhein, and aloe-emodin.[4] In fact, aloe-emodin, an anthraquinone from Da Huang (Radix et Rhizoma Rhei), has potent antibacterial activity and is effective against methicillin-resistant Staphylococcus aureus (MRSA).[5]

        Furthermore, Pueraria Clear Sinus utilizes many herbs with antiviral effects to treat the cause of the disease. Ge Gen (Radix Puerariae Lobatae) has an inhibitory effect on enterovirus 71 (EV71) when given before, simultaneously with, or after viral infection. Gui Zhi (Ramulus Cinnamomi) has an antiviral effect against influenza viruses.[6] Huang Qin (Radix Scutellariae) has a wide spectrum of antiviral activity. Specifically, baicalein and wogonin, two compounds from the herb, boost innate antiviral immunity by stimulating the production of cytokines and increasing the resistance to viral infection in human leukocytes.[7]

        Pueraria Clear Sinus also incorporates many herbs with antifungal effects to treat the cause of the disease. Xin Yi Hua (Flos Magnoliae) has an inhibitory effect on dermatomycoses.[8] Gui Zhi (Ramulus Cinnamomi) and Huang Qin (Radix Scutellariae) also have antifungal effect. Gui Zhi (Ramulus Cinnamomi) has a strong activity against murine oral candidiasis. Cinnamaldehyde, a compound from the plant, was the principal component responsible that inhibited the growth of Candida albicans. The researchers concluded that oral intake of a cassia preparation is a clinical candidate for a prophylactic or therapeutic tool against oral candida infection.[9] Huang Qin (Radix Scutellariae) has an in vivo antifungal effect against Candida albicans.[10]

        In addition, Pueraria Clear Sinus contains many herbs to treat allergy-induced rhinitis and sinusitis. Xin Yi Hua (Flos Magnoliae) has been used successfully for the management of allergic diseases. This herb shows an antiallergic effect by inducing mitochondria and caspase-dependent mast cell apoptosis.[11] In addition, Xin Yi Hua (Flos Magnoliae) and Bai Zhi (Radix Angelicae Dahuricae) have an antihistamine effect to inhibit histamine release and inflammation.[12],[13] Jie Geng (Radix Platycodonis) also has an antiallergic effect, as it acts by inhibiting the inflammatory cytokines and the signaling cascades, according to in vivo and in vitro studies.[14] Lastly, Huang Qin (Radix Scutellariae) shows a remarkable effect as an antiallergic agent. It inhibits histamine and leukotriene release from mast cells activated, with greater potency than Intal (cromolyn), a drug that prevents the release of inflammatory chemicals such as histamine from mast cells.[15]

        Since inflammation is a primary condition in both rhinitis (inflammation nasal mucous membrane) and sinusitis (inflammation of paranasal sinus), many herbs with anti-inflammatory effects are used in Pueraria Clear Sinus. Da Huang (Radix et Rhizoma Rhei) and Xin Yi Hua (Flos Magnoliae) exert their anti-inflammatory effects via inhibition of nitric oxide production.[16],[17] Huang Qin (Radix Scutellariae) has significant and potent anti-inflammatory properties via inhibition of nitric oxide, cyclo-oxygenase-2, prostaglandin E2, and proinflammatory cytokines.[18] Chuan Xiong (Rhizoma Chuanxiong) shows its anti-inflammatory effect by suppressing TNF-α production and bioactivity.[19] Bai Shao (Radix Paeoniae Alba) has a significant effect to decrease the secretion of monocyte chemotactic proteins (MCP-1 and MCP-3), two potent chemokines that mediate allergic nasal inflammation.[20] Lastly, Sheng Jiang (Rhizoma Zingiberis Recens) has several mechanisms for its anti-inflammatory effect. It has inhibitory effects on prostaglandin biosynthesis, similar to that of non-steroidal anti-inflammatory drugs. Furthermore, it suppresses prostaglandin synthesis through inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2. Lastly, ginger suppresses leukotriene biosynthesis by inhibiting 5-lipoxygenase.[21]

        Clinically, many herbs in Pueraria Clear Sinus have been used with great success to treat rhinitis and sinusitis. According to one study, 46 patients with chronic sinusitis were treated with an herbal formula with marked effectiveness in 35 cases, moderate improvement in 8 cases, and no response in 3 cases. The herbal formula was given in decoction, once daily, for seven days per course of treatment. The herbal formula contained Xin Yi Hua (Flos Magnoliae), Cang Er Zi (Fructus Xanthii), Chuan Xiong (Rhizoma Chuanxiong), Bai Zhi (Radix Angelicae Dahuricae) and others.[22] According to another study, 120 patients were treated with a 95% rate of effectiveness using an herbal formula with Xin Yi Hua (Flos Magnoliae) as the chief ingredient.[23] In addition to oral ingestion, topical application of herb also showed marked treatment effect. Topical application of essential oil of Xin Yi Hua (Flos Magnoliae) has been associated with reduction of mucous secretion, reduction of inflammation, and relief of nasal obstruction.[24] In fact, 1,576 patients with chronic sinusitis were treated with an 86.9% effective rate using topical application of an herbal formula made from Xin Yi Hua (Flos Magnoliae) and Cang Er Zi (Fructus Xanthii).[25] Finally, since many patients suffering from rhinitis and sinusitis will also have pain and headache, Bai Zhi (Radix Angelicae Dahuricae), Chuan Xiong (Rhizoma Chuanxiong), and Ge Gen (Radix Puerariae Lobatae) are added for their effect to treat headache and relieve pain.[26],[27],[28]

        In summary, Pueraria Clear Sinus is an excellent formula to treat the causes and the symptoms of rhinitis and sinusitis.

 

COMPARATIVE ANALYSIS

Sinusitis, rhinitis, and sinus infection are common nasal disorders. In Western medicine, these conditions are primarily treated with vasoconstrictive drugs that promote drainage, such as pseudoephedrine. Though effective, it is a strong stimulant and may cause many side effects, such as nervousness, restlessness, dizziness, difficulty sleeping, upset stomach, difficulty breathing, fast or irregular heartbeat, muscle weakness, palpitations, tremors, and hallucinations. In addition to vasoconstrictive drugs, antibiotic drugs may be used to address infectious sinusitis, rhinitis, and sinus infection. The main advantage of these two types of medications is that they are relatively effective, and reasonably safe, so long as they are prescribed correctly and monitored carefully.

        Sinusitis, rhinitis, and sinus infection are effectively treated with herbs that drain the sinus cavity, reduce nasal mucous secretions, and treat infection. These herbs may be given to treat acute or chronic infectious sinusitis and rhinitis. These herbs are very effective, and do not have the stimulating side effects that drugs have. Furthermore, antibiotic herbs are much safer and gentler than antibiotic drugs, and are able to treat infection without causing significant side effects or secondary infections. However, it is important to keep in mind that this formula is primarily a formula that treats sinusitis and rhinitis. Though it does have an antibiotic effect, its potency is only moderate, and may not be suitable in cases of severe sinus or respiratory tract infections.

        Both drugs and herbs are effective to treat sinusitis and rhinitis. In most cases, use of herbs is more than sufficient, as they effectively treat both conditions with little risk of side effects and adverse reactions. In cases of severe and stubborn sinus infection, additional therapies may be needed, such as antibiotic drugs or another antibiotic herbal formula.

 



[1] Xian Dai Zhong Yao Du Li Xue (Modern Toxicology of Chinese Materia Medica) 2005;63-65.

[2] Zhong Yao Xue (Chinese Herbology), 1988; 137:140.

[3] J Pharm Pharmacol 2000 Mar;52(3):361-6.

[4] Zhong Yao Xue (Chinese Herbology), 1998; 251:256.

[5] Hatano T, Kusuda M, Inada K, Ogawa TO, Shiota S, Tsuchiya T, Yoshida T. Effects of tannins and related polyphenols on methicillin-resistant Staphylococcus aureus. Phytochemistry. 2005 Sep;66(17):2047-55.

[6] Zhong Yao Xue (Chinese Herbology), 1998; 65:67.

[7] Błach-Olszewska Z, Jatczak B, Rak A, Lorenc M, Gulanowski B, Drobna A, Lamer-Zarawska E. Production of cytokines and stimulation of resistance to viral infection in human leukocytes by Scutellaria baicalensis flavones. Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland. J Interferon Cytokine Res. 2008 Sep;28(9):571-81.

[8] Zhong Yao Xue (Chinese Herbology), 1998; 84:85.

[9] Taguchi Y, Takizawa T, Ishibashi H, Sagawa T, Arai R, Inoue S, Yamaguchi H, Abe S. Therapeutic effects on murine oral candidiasis by oral administration of cassia (Cinnamomum cassia) preparation. Research and Product Development Division, S & B Foods Inc., Tokyo, Japan. Nippon Ishinkin Gakkai Zasshi. 2010;51(1):13-21.

[10] Wong KS, Tsang WK. In vitro antifungal activity of the aqueous extract of Scutellaria baicalensis Georgi root against Candida albicans. Int J Antimicrob Agents. 2009 Sep;34(3):284-5.

[11] Kim G.C., Lee S.G., Park B.S., Kim J.Y., Song Y.S., Kim J.M., Yoo K.S., Huh G.Y., Jeong M.H., Lim Y.J., Kim H.M. & Yoo Y.H. Magnoliae flos induces apoptosis of RBL-2H3 cells via mitochondria and caspase. Int Arch Allergy Immunol. 2003 Jun;131(2):101-10.

[12] Shen Y, Pang EC, Xue CC, Zhao ZZ, Lin JG, Li CG. Inhibitions of mast cell-derived histamine release by different Flos Magnoliae species in rat peritoneal mast cells. RMIT Chinese Medicine Research Group, School of Health Sciences, RMIT University, Victoria, Australia. Phytomedicine. 2008 Oct;15(10):808-14.

[13] Chen Y., Fan G., Chen B., Xie Y., Wu H., Wu Y., Yan C. & Wang J. Separation and quantitative analysis of coumarin compounds from Angelica dahurica (Fisch. ex Hoffm) Benth. et Hook. f by pressurized capillary electrochromatography. J Pharm Biomed Anal. 2006, 41(1): 105-116.

[14] Han EH, Park JH, Kim JY, Chung YC, Jeong HG. Inhibitory mechanism of saponins derived from roots of Platycodon grandiflorum on anaphylactic reaction and IgE-mediated allergic response in mast cells. BK21 Project Team, Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju, South Korea. Food Chem Toxicol. 2009 Feb 4.

[15] Kim DS, Son EJ, Kim M, Heo YM, Nam JB, Ro JY, Woo SS. Antiallergic herbal composition from Scutellaria baicalensis and Phyllostachys edulis. Unigen Inc., Cheonan, 330-863 Chungnam, Korea. Planta Med. 2010 May;76(7):678-82.

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