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CA Support


CLINICAL APPLICATIONS

* Cancer support formula: patients with cancer who suffer extreme weakness and deficiency and cannot withstand surgery or chemotherapy and radiation treatments

* Late stage, terminally-ill cancer patients with pain and suffering

* Maintainance and preventative formula to be used at the conclusion of chemotherapy and radiation treatments

 

WESTERN THERAPEUTIC ACTIONS

* Immunostimulant effect to boost white blood cells

* Hematopoietic function to increase red blood cells

* Antineoplastic activity to suppress cancer cells

* Antiangiogenic property to inhibit tumor growth, invasion, and metastasis

 

CHINESE THERAPEUTIC ACTIONS

* Clears heat

* Eliminates toxins

* Tonifies the underlying deficiencies (qi, blood, yin and yang)

 

DOSAGE

Take 3 to 4 capsules three times daily. It should be taken on an empty stomach with warm water for maximum effectiveness.

 

INGREDIENTS


Bai Hua She She Cao (Herba Hedyotis)

Bai Zhu (Rhizoma Atractylodis Macrocephalae)

Ban Zhi Lian (Herba Scutellariae Barbatae)

Chong Lou (Rhizoma Paridis)

Dong Chong Xia Cao (Cordyceps)

E Zhu (Rhizoma Curcumae)

Fu Ling (Poria)

Huang Jing (Rhizoma Polygonati)

Huang Qi (Radix Astragali)

Ji Xue Teng (Caulis Spatholobi)

Xi Yang Shen (Radix Panacis Quinquefolii)

Yi Yi Ren (Semen Coicis)


 

BACKGROUND

Cancer is the second leading cause of death, according to a report by CDC published in January 11, 2012.[1] In Western medicine, treatment options for cancer include surgery, chemotherapy and radiation. Though these treatments may be effective, they are invasive to the body and often cause severe and serious damage to many organs and cells. Therefore, additional interventions are extremely important to alleviate the side effects of these invasive treatments, support the body and its health, and improve the overall quality of life.

 

FORMULA EXPLANATION

CA Support is developed specifically for individuals who have extreme weakness and deficiency after prolonged battles with cancer and its treatments (chemotherapy and radiation). This condition is characterized by both extreme excess (cancer is often considered as accumulation of phlegm, heat, and toxins) and extreme deficiency (qi, blood, yin and yang deficiencies caused by chemotherapy and radiation). Therefore, optimal treatment requires use of herbs to gently clear heat and eliminate toxins, and greatly tonify the underlying deficiencies.

        In this formula, Huang Qi (Radix Astragali) and Xi Yang Shen (Radix Panacis Quinquefolii) are both used to greatly tonify qi. Both tonics are light, and have very strong immune-enhancing effects. Though potent, they do not create the general stagnating side-effects associated with tonics. Bai Zhu (Rhizoma Atractylodis Macrocephalae), Fu Ling (Poria), and Yi Yi Ren (Semen Coicis) strengthen the middle jiao, and further enhance the qi-tonifying effect of Huang Qi (Radix Astragali) and Xi Yang Shen (Radix Panacis Quinquefolii). By strengthening the middle jiao, the digestive system can function properly and appetite will increase. Ji Xue Teng (Caulis Spatholobi) tonifies blood, Huang Jing (Rhizoma Polygonati) nourishes yin, and Dong Chong Xia Cao (Cordyceps) strengthens yang. Together, these herbs tonify and treat the underlying qi, blood, yin and yang deficiencies. Small amounts of E Zhu (Rhizoma Curcumae), Chong Lou (Rhizoma Paridis), Ban Zhi Lian (Herba Scutellariae Barbatae) and Bai Hua She She Cao (Herba Hedyotis) are added to clear heat, relieve pain, and eliminate toxins. These three herbs also have shown promising anticancer effects according to various in vitro and in vivo studies.[2],[3]

        In summary, CA Support is developed specifically to address the difficult and challenging cases of cancer in which the patients are too weak to continue with chemotherapy and/or radiation treatments. Use of this formula will strengthen the underlying constitution, improve quality of life, and decrease pain and suffering.

 

CAUTIONS & CONTRAINDICATIONS

* This formula is not designed to treat cancer, nor is it designed to replace chemotherapy and/or radiation. The focus of this formula is to support patients with cancer who are too weak to continue with chemotherapy and radiation treatments. This formula contains herbs that tonify the underlying deficiencies to improve quality of life and reduce pain and suffering.

* This formula is contraindicated in patients with severe infection or inflammation with excess heat.

 

CLINICAL NOTE

* Chinese or Korean Ren Shen (Radix et Rhizoma Ginseng) should not be used in individuals who suffer from extreme weakness and deficiency from chemotherapy and radiation treatments. These individuals often have severe yin deficiency, and use of a warm herb [such as Ren Shen (Radix et Rhizoma Ginseng)] may create more side effects such as dry nose and mouth, nosebleeds and ulcerations in the mouth. Therefore, American Xi Yang Shen (Radix Panacis Quinquefolii) will be much more beneficial and is the herb used in this formula instead of Ren Shen (Radix et Rhizoma Ginseng).

 

Pulse Diagnosis by Dr. Jimmy Wei-Yen Chang:

* Tent pulse, a convex-shaped pulse that collapses under pressure

 

SUPPLEMENTARY FORMULAS

* To enhance the immune system and increase white blood cell count, take with Cordyceps 3 or Immune +.

* To increase red blood cell count, add Dang Gui Bu Xue Tang (Tangkuei Decoction to Tonify the Blood) or Schisandra ZZZ.

* For hair loss from chemotherapy or radiation, take with Polygonum 14.

* For loose stools because of Spleen deficiency, add GI Tonic.

* For pain due to cancer, add Herbal ANG.

* With acute headache, add Corydalin (AC).

* With chronic headache, add Corydalin (CR).

* For dry skin, add Nourish (Fluids).

 

ACUPUNCTURE TREATMENT

Traditional Points:

* Zusanli (ST 36)

* Patients in many cases are too weak to receive acupuncture. It is recommended to just perform gentle massage or acupressure.

 

Classic Master Tung's Points:

* Bladder cancer/tumor: Simazhong (T 88.17), Tongshen (T 88.09), Wanshunyi (T 22.08), Tianhuangfu [Shenguan] (T 77.18), Shuangling (T 11.28)*, Waisanguan (T 77.27), Zhiwu (T 11.26)  

* Bone cancer/tumor: Bilateral Simashang (T 88.18), Simazhong (T 88.17), Simaxia (T 88.19), Minghuang (T 88.12), Tianhuang (T 88.13), Qihuang (T 88.14), Shuangling (T 11.28)*, Tianhuangfu [Shenguan] (T 77.18), Zhiwu (T 11.26). Needle everyday. Bleed HT and LU area below the knee. The more the blood is let out, the better the result.

* Brain cancer/tumor: Shangliu (T 55.06), Zhengjin (T 77.01), Zhengzong (T 77.02) with strong stimulation, Yizhong (T 77.05), Erzhong (T 77.06), Sanzhong (T 77.07), Shuangling (T 11.28)*, Zhiwu (T 11.26). Bleed dark veins nearby the medial malleolus or Shuijing (T 66.13). Bleed before needling for best result.

* Breast cancer/tumor: Simashang (T 88.18), Simazhong (T 88.17), Simaxia (T 88.19), Yizhong (T 77.05), Erzhong (T 77.06), Sanzhong (T 77.07), Shuanglongyi (T 77.29)*, Shuanglonger (T 77.30)*, Zhiwu (T 11.26). Bleed all dark veins nearby the HT, LU area on the legs [maximum of 150 mL for each time of bleeding]. Bleed before needling for best result.

* Chondroma: Simashang (T 88.18), Simazhong (T 88.17), Dihuang (T 77.19), Renhuang (T 77.21), Tianhuangfu [Shenguan] (T 77.18), Fuyuan (T 11.22), Shuangling (T 11.28), Zhiwu (T 11.26). Bleed the affected area. Bleed before needling for best result.

* Colon cancer/tumor: Sanzhong (T 77.07), Zuwujin (T 77.25), Zuqianjin (T 77.24), Tianhuang (T 88.13), Minghuang (T 88.12), Cesanli (T 77.22), Simazhong (T 88.17), Shuangling (T 11.28)*, Zhiwu (T 11.26). Bleed Sihuashang (T 77.08), Sihuazhong (T 77.09), Sihuaxia (T 77.11), Fuchang (T 77.12), or dark veins nearby. Bleed the LU area below the knee. Bleed before needling for best result. The more the blood is let out, the better the effect.

* Fallopian tube cancer/tumor: Fuke (T 11.24), Huanchao (T 11.06), Sanzhong (T 77.07), Jiemeiyi (T 88.04), Jiemeier (T 88.05), Jiemeisan (T 88.06), Shuangling (T 11.28)*, Zhiwu (T 11.26). Bleed dark veins nearby Daling (PC 7), Yinxi (HT 6). Bleed before needling for best result. The more the blood is let out, the better the effect.

* Gallbladder cancer/tumor: Minghuang (T 88.12), Qihuang (T 88.14), Huozhi (T 88.15), Shuangling (T 11.28)*, Zhiwu (T 11.26)  

* Kidney cancer/tumor: Tianhuang (T 77.17), Dihuang (T 77.19), Renhuang (T 77.21), Tongshen (T 88.09), Wanshunyi (T 22.08), Shuangling (T 11.28)*, Zhiwu (T 11.26)  

* Liver cancer/tumor: Minghuang (T 88.12), Tianhuang (T 88.13), Qihuang (T 88.14), Huoying (T 66.03), Tianhuangfu [Shenguan] (T 77.18), Shuangling (T 11.28)*, Zhiwu (T 11.26). Needle everyday.

* Lung cancer/tumor: Simashang (T 88.18), Simazhong (T 88.17), Simaxia (T 88.19), Linggu (T 22.05), Dabai (T 22.04), Shuangling (T 11.28)*, Waisanguan (T 77.27), Xinchang (T 11.19), Zhiwu (T 11.26). Bleed the LU area below the knee. Bleed before needling for best result. The more the blood is let out, the better the effect.

* Lymphatic cancer/tumor: Wanshunyi (T 22.08), Yizhong (T 77.05), Erzhong (T 77.06), Sanzhong (T 77.07), Cesanli (T 77.22), Tianhuangfu [Shenguan] (T 77.18), Huoying (T 66.03), Shuangling (T 11.28)*, Zhiwu (T 11.26). Bleed the LU area below the knee. The more the blood is let out, the better the effect.

* Nasal cancer/tumor: Linggu (T 22.05), Dabai (T 22.04), Simashang (T 88.18), Simazhong (T 88.17), Simaxia (T 88.19), Fugesan (T 44.30)*, Shuangling (T 11.28)*, Zhiwu (T 11.26). Bleed the LU area below the knee. Bleed before needling for best result. The more the blood is let out, the better the effect.

* Oral cancer/tumor: Bleed Shaoshang (LU 11), Sihuazhong (T 77.09), mouth area, Zhiwu (T 11.26). Bleed before needling for best result. The more the blood is let out, the better the effect.

* Osteosarcoma: Piyi (T 88.35)*, Pier (T 88.36)*, Simazhong (T 88.17), Tianhuangfu [Shenguan] (T 77.18), Huoying (T 66.03), Fuyuan (T 11.22), Shuangling (T 11.28)*, Zhiwu (T 11.26). Bleed around affected area. The more blood that is let out, the better the result.

* Ovarian, uterus, cervix cancer/tumor: Fuke (T 11.24), Huanchao (T 11.06), Zhiwu (T 11.26), Shuangling (T 11.28)*, Qimen (T 33.01), Qijiao (T 33.02), Qizheng (T 33.03), Yunbai (T 44.11), Menjin (T 66.05), Waisanguan (T 77.27), Tianhuang (T 77.17), Dihuang (T 77.19), Renhuang (T 77.21), Jiemeiyi (T 88.04), Jiemeier (T 88.05), Jiemeisan (T 88.06), Mufu (T 88.38)*, Tongshen (T 88.09), Tongbei (T 88.11). Bleed the dark veins nearby the web between the first and second toes; and the second and third toes. Bleed sacral area with cupping. Bleed before needling for best result. The more the blood is let out, the better the effect.

* Pancreatic cancer/tumor: Piyi (T 88.35)*, Pier (T 88.36)*, Pisan (T 88.37)*, Yizhong (T 77.05), Erzhong (T 77.06), Sanzhong (T 77.07), Minghuang (T 88.12), Qihuang (T 88.14), Shuangling (T 11.28)*, Zhiwu (T 11.26)

* Stomach cancer/tumor: Cesanli (T 77.22), Waisanguan (T 77.27), Shuangling (T 11.28)*, Zhiwu (T 11.26). Bleed dark veins nearby the ST area in the lower limb. Bleed before needling for best result. The more the blood is let out, the better the effect.   

* Testicular cancer/tumor: Dajian (T 11.01), Xiaojian (T 11.02), Waijian (T 11.04), Fujian (T 11.03), Shuangling (T 11.28)*, Zhiwu (T 11.26)   

* Throat cancer/tumor: Tongguan (T 88.01), Cesanli (T 77.22), Yizhong (T 77.05), Erzhong (T 77.06), Sanzhong (T 77.07), Linggu (T 22.05), Dabai (T 22.04), Sihuashang (T 77.08), Zuqianjin (T 77.24), Zuwujin (T 77.25), Waisanguan (T 77.27), Shuangling (T 11.28)*, Zhiwu (T 11.26). Bleed dark veins nearby Shaoshang (LU 11), nine points evenly on the neck, or the back of the neck or the ST channel on the lower limb. Bleed before needling for best result. The more the blood is let out, the better the effect.

* Thyroid cancer/tumor: Xinling (T 33.17)*, Simashang (T 88.18), Simazhong (T 88.17), Simaxia (T 88.19), Waisanguan (T 77.27), Shuangling (T 11.28)*, Zhiwu (T 11.26). Bleed Sihuazhong (T 77.09) and back of the neck. Bleed before needling for best result. The more the blood is let out, the better the effect.

* Tongue cancer/tumor: Cesanli (T 77.22), Houjian (T 44.29)*, Minghuang (T 88.12), Qihuang (T 88.14), Shuangling (T 11.28)*, Zhiwu (T 11.26). Bleed the LU area below the knee. Bleed before needling for best result. The more the blood is let out, the better the effect.

* Vaginal cancer/tumor: Fuke (T 11.24), Huanchao (T 11.06), Libai (T 44.12), Yunbai (T 44.11), Sanzhong (T 77.07), Shuangling (T 11.28)*, Zhiwu (T 11.26). Bleed dark veins nearby Daling (PC 7), Yinxi (HT 6). Bleed before needling for best result. The more the blood is let out, the better the effect.

 

Master Tung’s Points by Dr. Chuan-Min Wang:

* Terminal cancer: Yizhong (T 77.05), Erzhong (T 77.06), Sanzhong (T 77.07), Waisanguan (T 77.27)

 

Balance Method by Dr. Richard Tan:

* Left side: Hegu (LI 4), Zusanli (ST 36), Taixi (KI 3), Yinlingquan (SP 9)

* Right side: Lieque (LU 7), Tongli (HT 5), Zusanli (ST 36)

* Left and right side can be alternated from treatment to treatment.

 

Auricular Medicine by Dr. Li-Chun Huang:

* Fatigue: Sympathetic, Kidney, Liver, Spleen, San Jiao, Anxious, Nervous Subcortex, Speed Recovered Fatigue. Bleed Ear Apex.

* Promoting immunity: Allergic Area, Endocrine, Adrenal Gland, Spleen, Liver. Bleed Ear Apex and Helix 1-6.

 

NUTRITION

* Eat a variety of fresh, organic fruits and vegetables of all colors. 

* Incorporate more high fiber whole grains and nuts into the diet.

* Drink warm or hot liquids with meals. Putting cold and ice on any part of the body will immediately constrict the flow of blood to that region. Similarly, drinking cold or iced drinks with meals will hinder the natural peristaltic movements of the digestive system.

* Foods with antioxidant effects, such as vitamin A, C and E are beneficial as they neutralize the free radicals and minimize damage to cells. Beneficial foods include citrus fruits, carrots, green leafy vegetables, and green tea.

* Chew food completely and thoroughly. The digestive tract can process and absorb smaller pieces of food much better than food that is incompletely chewed. Larger pieces of food can lead to incomplete digestion and digestive discomfort.

* Always eat breakfast. According to the TCM clock, the most optimal time for the digestive system is in the morning from 8 to 10 a.m.

* Give the body two to three hours between the last meal of the day and bedtime. During sleep, the digestive system slows down as well. Make sure the body has adequate time to digest the food before going into sleep mode.

* If the patient is allergic to any food or feels uncomfortable after eating certain foods, avoid eating them.

* Avoid fast food, processed foods, junk food, artificial sugars, and carbonated drinks. Stay away from meat, greasy food, alcohol, caffeine, dairy products (except for unsweetened low-fat yogurt), tap water, iron supplements and vegetables and fruits with pesticides.

* For patients who have breast cancer, the following foods are especially beneficial: all mushrooms, whole grains, broccoli, brussel sprouts, cabbage, cauliflower, yellow/orange vegetables (carrots, pumpkins, squash, sweet potatoes), fresh garlic, onions, fresh berries, apples, cherries, grapes, and plums.

* Ginger can always be used to relieve nausea. Boil ten slices of ginger for five minutes and mix with brown sugar. Slices of fresh ginger can also be chewed or sucked on for a stronger and immediate effect.

* The Spleen is responsible for generating post-natal qi and good Spleen function also contributes to a healthy immune system. Foods that damage the Spleen should be avoided:

§ Avoid any and all foods that contain sugar, such as cake, dessert, candy, chocolate, canned juice, soft drinks, caffeinated drinks, stevia, sugar substitutes, agave, xylitol, and corn syrup.

§ Avoid raw or uncooked meats, such as sashimi, sushi, steak tartar, and seared meat. Minimize consumption of foods that are cooling in nature, including tofu, tomato, celery, asparagus, bamboo, seaweed, kelp, bitter melon, cucumber, gourd, luffa, eggplant, winter melon, watermelon, honeydew, citrus, oranges, guava, grapefruit, pineapple, plums, pear, banana, papaya, watermelon, white radish, mustard leaf, potherb mustard, Chinese Kale, napa, bamboo sprout. Do not eat foods straight from the refrigerator. Long-term intake of cold fruits and vegetables like the ones listed above may be damaging to the Spleen. The cooling property of foods can be neutralized by cooking or adding 20 pieces of Gou Qi Zi (Fructus Lycii).

§ Avoid carbohydrates like white rice or bread as they may produce dampness.

§ No seafood especially shellfish, like crabs, oyster, scallops, clams, lobster and shrimp (they enter the yangming Stomach channel).

§ Avoid fermented foods like cheese or fermented tofu.

§ Do not eat dairy products, such as milk, cream, yogurt, cheese, and ice cream.

§ No lamb, beef, goose or duck.

§ Avoid fried or greasy foods.

* Warm and hot natured foods that damage qi and yin should be avoided, such as:

§ Avoid certain fruits like mango and durian that produce heat.

§ Avoid spicy foods and stimulants like coffee, alcohol, and energy drinks.

§ Avoid spicy/pungent/aromatic vegetables such as pepper, garlic, onions, basil, rosemary, cumin, funnel, anise, leeks, chives, scallions, thyme, saffron, wormwood, mustard, chili pepper, and wasabi.

* Avoid food and drinks with artificial coloring.

* Consume as few meat products as possible. Do not eat processed meats, such as lunch meats, hot dogs and sausages, as they contain nitrites that are associated with inflammation and chronic disease.

* Patients are encourages to eat millet porridge with dioscorea and poria daily for breakfast. Millet has been used for the military traditionally in the past and the present. It has high nutritional value, is easy to digest, and extremely beneficial to the Spleen. The millet porridge contains the following ingredients: millet 100 grams, Shan Yao (Rhizoma Dioscoreae) 50 grams for fresh root or 25 grams for dried root, and Fu Ling (Poria) 25 grams. Cook all ingredients in 4 cups of water. Bring it to a boil for 5 minutes, and simmer on medium fire for 20 minutes.

 

The Tao of Nutrition by Dr. Maoshing Ni and Cathy McNease:

* Consume foods that help strengthen the body so that it is able to fight against the cancer cells. A detoxifying diet is also recommended to rid the body of the toxin (cancer cells).

* Blend shiitake or ganoderma mushrooms and white fungus, boil and drink the soup three times daily.

* Boil together mung beans, pearl barley, azuki beans, and figs. This makes a delicious dessert that will aid appetite and sustain energy level.

* Make tea from dandelion, burdock, and chrysanthemum flowers; also can add beet tops or carrot tops. Drink this as the regular beverage every day.

* Always wash commercially grown fruits and vegetables in salt water to neutralize chemicals.

* Eat garlic and seaweed, slightly stir-fried in water.

* Drink carrot and celery juice.

* Make blender juice from a mixture of fresh vegetables and drink warm.

* For breast cancer, make tea from asparagus and dandelion and apply poultice to breast.

* For breast tumor, charcoal the pumpkin cap into powder, take one teaspoon of powder in one small glass of rice wine twice daily.

* Make tea from seaweed, peach kernel, and green orange peels.

* For externally visible tumors, make a poultice from seaweed, ginger and dandelion, and apply locally.

* Avoid the following foods: meat (a little fish can be eaten), coffee, cinnamon, anise, pepper, dairy products, spicy foods (except garlic), high fat foods, cooked oils, chemical additives, and moldy foods.

* Avoid smoking, stress, and all irritants.

 

LIFESTYLE INSTRUCTIONS

* Avoid radiation from microwaves and limit prolonged exposure to appliances with high electromagnetic output, such as television, computer monitors, electric stoves, cellular phones, and other popular electronic devices.

* Relax, exercise regularly (tai chi chuan * tai ji quan], qi gong or yoga). Maintain a positive outlook on life.

* Avoid consumption of alcohol and exposure to tobacco in any form.

* Avoid stress and anxiety whenever possible. They suppress the immune system, slow down the metabolic process, and foster the development of cancer.

* Avoid wearing tight bras that can cut off lymphatic flow, obstruct elimination of toxins and increase risk of tumor growth.

* Sleep by 10:00 p.m. In TCM, 11:00 p.m. to 1:00 a.m. is when the yin shifts to yang. It is crucial for the body to be at rest during this time for optimal health.

 

PHARMACOLOGICAL AND CLINICAL RESEARCH

CA Support is developed specifically for individuals who have extreme weakness and deficiency after prolonged battles with cancer and its treatments (chemotherapy and radiation). At this moment, though the patient still has cancer, their constitution is too fragile to continue with chemotherapy and radiation. Optimal treatment requires use of herbs to suppress the growth of cancer cells while stimulating the production of healthy cells. To achieve this goal, CA Support uses herbs with immunostimulant effects to increase white blood cells, hematopoietic effects to increase red blood cells, and antineoplastic effects to suppress cancer cells.

        Huang Qi (Radix Astragali), one of the most commonly used herbs, has been shown in many clinical studies to effectively increase white blood cells, multinuclear leukocytes, and IgM.[4],[5] Use of Huang Qi (Radix Astragali) has been shown to restore normal immune system function in 115 patients with leukopenia.[6] Furthermore, use of Huang Qi (Radix Astragali) is also associated with a marked hematopoietic effect, as it stimulates the bone marrow and increases the production and maturity of blood cells.[7] In addition to Huang Qi (Radix Astragali), CA Support contains many other herbs with immunostimulant effects. Ji Xue Teng (Caulis Spatholobi) has been shown to increase both neutrophils and eosinophils after three days of the herbal therapy.[8] Ji Xue Teng (Caulis Spatholobi) also has a hematopoietic effect to distinctly stimulate the proliferation of hematopoietic progenitor cells in subjects with bone marrow depression.[9] Dong Chong Xia Cao (Cordyceps) is another herb that has demonstrated immunomodulatory functions. It enhances the overall immunity by increasing the number of lymphocytes and natural killer cells, and the production of interleukin, interferon and tumor-necrosis-factor.[10],[11],[12],[13],[14] Cordysinocan, a polysaccharide isolated from cultured Dong Chong Xia Cao (Cordyceps), activates immune responses in cultured T-lymphocytes and macrophages to signal the cascade and induction of cytokines.[15] Bai Zhu (Rhizoma Atractylodis Macrocephalae) increases the number of white blood cells, lymphocytes, and IgG, as well as enhancing the activity of macrophages and the reticuloendothelial system.[16],[17] Chong Lou (Rhizoma Paridis) exerts a stimulating effect on the immune system in relation to phagocytosis, respiratory burst, and nitric oxide production.[18] Finally, Bai Hua She She Cao (Herba Hedyotis) has both immunomodulatory and antitumor effects by stimulating the immune system to kill or engulf tumor cells.[19]

        In addition to strengthening the body, CA Support also incorporates many herbs with antineoplastic effects to fight cancer. Ban Zhi Lian (Herba Scutellariae Barbatae) and Bai Hua She She Cao (Herba Hedyotis) have potent antineoplastic effects, and have shown a promising effect to treat various types of cancer according to both in vitro and in vivo studies.[20],[21] Clinical applications of Ban Zhi Lian (Herba Scutellariae Barbatae) and Bai Hua She She Cao (Herba Hedyotis) include: breast cancer,[22],[23] liver cancer,[24],[25] nasopharyngeal cancer,[26] colorectal cancer,[27] leukemia,[28] prostate cancer,[29] lung cancer,[30] uterine leiomyoma,[31] skin cancer,[32] and many others. E Zhu (Rhizoma Curcumae) has a marked antineoplastic effect to induce apoptosis and inhibits proliferation of human cancer cells.[33],[34] It has been used with satisfactory results for treatment of stomach, lung, liver, and esophageal cancers.[35] Dong Chong Xia Cao (Cordyceps) has a cytotoxic effect, and shows a significant and dose-dependent inhibitory effect on the proliferation of four cancer cell lines: breast cancer, mouse melanoma, human premyelocytic leukemia, and human hepatocellular carcinoma.[36] Chong Lou (Rhizoma Paridis) has a dose-dependent anticancer activity against lung adenocarcinoma cells,[37] human promyelocytic leukemia cells,[38] and breast cancer cells.[39] Bai Zhu (Rhizoma Atractylodis Macrocephalae) has marked inhibitory action against esophageal cancer according to several in vitro studies.[40] Yi Yi Ren (Semen Coicis) and Fu Ling (Poria) have antineoplastic activity, and are generally more effective when combined with other therapies.[41],[42] Lastly, E Zhu (Rhizoma Curcumae) and Fu Ling (Poria) have antiangiogenic activity, which inhibit the formation of new blood vessels from a pre-existing vascular network to suppress tumor growth, invasion, and metastasis.[43],[44]

        Overall, CA Support is developed specifically to address the difficult and challenging cases of cancer in which the patient is too weak to continue with chemotherapy and radiation treatments. Use of CA Support will strengthen the underlying constitution and suppress the growth of cancer cells. In conclusion, CA Support is an excellent formula to decrease pain and suffering, and improve quality of life for patients with cancer.

 

COMPARATIVE ANALYSIS

Despite all the advances in medicine, treatment of cancer is still in its infancy in both Western and traditional Chinese medicine.

        Optimal treatment methods may include chemotherapy, radiation, and/or surgery. Though they may be effective, they are extremely harsh and create a tremendous number of side effects, including severe nausea, vomiting, hair loss, and most importantly, bone marrow suppression with decreased count of red and white blood cells. Serious cases of bone marrow suppression often necessitate the termination of chemotherapy and radiation treatments, a scenario where the patient now suffers from both cancer and the side effects of its treatments at the same time.

        For patients with cancer who are too weak to receive chemotherapy, radiation, and/or surgery, use of herbal therapies is extremely beneficial to alleviate the side effects of drugs, strengthen the body, and improve overall quality of life.

        Optimal therapy in cases of cancer is not to choose between Western or traditional Chinese medicine, but to use Western and traditional Chinese medicines together. These two modalities of medicine complement each others, and provide the brightest outlook and prognosis for successful treatment of cancer.

 



[1] Center of Disease Control and Prevention (CDC). National Vital Statistics Report. Volume 60, Number 4. January 11, 2012.

[2] Wong BY, Lau BH, Jia TY, Wan CP. Oldenlandia diffusa and Scutellaria barbata augment macrophage oxidative burst and inhibit tumor growth. Cancer Biother Radiopharm 1996 Feb; 11(1):51-6.

[3] Wong BY, Lau BH, Jia TY, Wan CP. Oldenlandia diffusa and Scutellaria barbata augment macrophage oxidative burst and inhibit tumor growth. Cancer Biother Radiopharm 1996 Feb; 11(1):51-6.

[4] Shan Xi Yi Yao Za Zhi (Shanxi Journal of Medicine and Herbology), 1974; 5-6:57.

[5] Biol Pharm Bull, 1977; 20(11)-1178-82.

[6] Zhong Guo Zhong Xi Yi Jie He Za Zhi (Chinese Journal of Integrative Chinese and Western Medicine), 1995 Aug.; 15(8):462-4.

[7] Nan Jing Zhong Yi Xue Yuan Xue Bao (Journal of Nanjing University of Traditional Chinese Medicine), 1989; 1:43.

[8] Shang Hai Zhong Yi Yao Za Zhi (Shanghai Journal of Chinese Medicine and Herbology), 1965; 9:16.

[9] Wang DX, Chen ML, Yin JF, Liu P. Effect of SS8, the active part of Spatholobus suberectus Dunn, on proliferation of hematopoietic progenitor cells in mice with bone marrow depression. Zhongguo Zhong Yao Za Zhi. 2003 Feb;28(2):152-5.

[10] Kuo,YC. et al. Cordyceps sinensis as an immuno-modulatory agent. American Journal Of Chinese Medicine. 24(2):111-25, 1996.

[11] Guan, YJ. et al. Effect of cordyceps sinensis on T-lymphocyte subsets in chronic renal failure. Chung-Kuo Chung His I Chieh Ho Tsa Chih. Jun. 1992; 12(6):338-9,323.

[12] Liu, C. et al. Effects of cordyceps sinensis (CS) on in vitro natural killer cells. Chung-Kuo Chung His I Chieh Ho Tsa Chih. May. 1992; 12(5):267-9,259.

[13] Xu, RH. et al. Effects of cordyceps sinensis on natural killer activity and colony formation of B16 melanoma. Chinese Medical Journal. Feb. 1992; 105(2):97-101.

[14] Liu, P. et al. Influence of cordyceps sinensis (berk.) sacc. and rat serum containing same medicine on IL-1, IFN and TNF produced by rat Kupffer's cells. Chung Kuo Chung Yao Tsa Chih, June 1996; 21(6):367-9, 384.

[15] Cheung JK, Li J, Cheung AW, Zhu Y, Zheng KY, Bi CW, Duan R, Choi RC, Lau DT, Dong TT, Lau BW, Tsim KW. Cordysinocan, a polysaccharide isolated from cultured Cordyceps, activates immune responses in cultured T-lymphocytes and macrophages: signaling cascade and induction of cytokines. J Ethnopharmacol. 2009 Jul 6;124(1):61-8.

[16] Xin Yi Yao Xue Za Zhi (New Journal of Medicine and Herbology), 1979; 6:60.

[17] Jun Shi Yi Xue Jian Xun (Military Medicine Notes), 1977; 2:5.

[18] Zhang XF, Cui Y, Huang JJ, Zhang YZ, Nie Z, Wang LF, Yan BZ, Tang YL, Liu Y. Immuno-stimulating properties of diosgenyl saponins isolated from Paris polyphylla. State Key laboratory for SCUSS, Institute of Chemistry, The Chinese Academy of Sciences, Beijing 100080, China. Bioorg Med Chem Lett. 2007 May 1;17(9):2408-13.

[19] Shan BE, Zhang JY, Du XN. Immunomodulatory activity and anti-tumor activity of Oldenlandia diffusa in vitro. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2001 May;21(5):370-4.

[20] Wong BY, Lau BH, Jia TY, Wan CP. Oldenlandia diffusa and Scutellaria barbata augment macrophage oxidative burst and inhibit tumor growth. Cancer Biother Radiopharm 1996 Feb; 11(1):51-6.

[21] Wong BY, Lau BH, Jia TY, Wan CP. Oldenlandia diffusa and Scutellaria barbata augment macrophage oxidative burst and inhibit tumor growth. Cancer Biother Radiopharm 1996 Feb; 11(1):51-6.

[22] Liu Z, Liu M, Liu M, Li J. Methylanthraquinone from Hedyotis diffusa WILLD induces Ca(2+)-mediated apoptosis in human breast cancer cells. Toxicol In Vitro. 2010 Feb;24(1):142-7.

[23] Fong S, Shoemaker M, Cadaoas J, Lo A, Liao W, Tagliaferri M, Cohen I, Shtivelman E. Molecular mechanisms underlying selective cytotoxic activity of BZL101, an extract of Scutellaria barbata, towards breast cancer cells. Cancer Biol Ther. 2008 Apr;7(4):577-86.

[24] Yu Hsueh-Chiu, Suzuki S., Okubo T., Kawashima I., Tsuda M., Borai N.E., Yamamura M. & Yu H.C. Anti-tumor effect of Chinese herbal medicines " Scutellaria barbata and Oldenlandia diffusa " on cancer cell lines and C3H-AVy mouse with spontaneous hepatocellular carcinoma. J of Traditional Medicines. 2000, 17: 165-169.

[25] Tang PM, Chan JY, Au SW, Kong SK, Tsui SK, Waye MM, Mak TC, Fong WP, Fung KP. Pheophorbide a, an active compound isolated from Scutellaria barbata, possesses photodynamic activities by inducing apoptosis in human hepatocellular carcinoma. Cancer Biol Ther. 2006 Sep;5(9):1111-6.

[26] Dai SJ, Peng WB, Zhang DW, Shen L, Wang WY, Ren Y. Cytotoxic neo-clerodane diterpenoid alkaloids from Scutellaria barbata. J Nat Prod. 2009 Oct;72(10):1793-7.

[27] Dai SJ, Liang DD, Ren Y, Liu K, Shen L. New neo-clerodane diterpenoid alkaloids from Scutellaria barbata with cytotoxic activities. Chem Pharm Bull (Tokyo). 2008 Feb;56(2):207-9.

[28] Ren Min Wei Sheng Chu Ban She (Journal of People's Public Health), 1988:302.

[29] Wong BY, Nguyen DL, Lin T, Wong HH, Cavalcante A, Greenberg NM, Hausted RP, Zheng J. Chinese medicinal herb Scutellaria barbata modulates apoptosis and cell survival in murine and human prostate cancer cells and tumor development in TRAMP mice. Eur J Cancer Prev. 2009 Aug;18(4):331-41.

[30] Chen LG, Hung LY, Tsai KW, Pan YS, Tsai YD, Li YZ, Liu YW. Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells. Mol Nutr Food Res. 2008 Nov;52(11):1349-57.

[31] Kim KW, Jin UH, Kim DI, Lee TK, Kim MS, Oh MJ, Kim MS, Kwon DY, Lee YC, Kim CH. Antiproliferative effect of Scutellaria barbata D. Don. on cultured human uterine leiomyoma cells by down-regulation of the expression of Bcl-2 protein. Phytother Res. 2008 May;22(5):583-90.

[32] Suh SJ, Yoon JW, Lee TK, Jin UH, Kim SL, Kim MS, Kwon DY, Lee YC, Kim CH. Chemoprevention of Scutellaria bardata on human cancer cells and tumorigenesis in skin cancer. Phytother Res. 2007 Feb;21(2):135-41.

[33] Xin Yi Yao Xue Za Zhi (New Journal of Medicine and Herbology), 1976; 12:28.

[34] Lim CB, Ky N, Ng HM, Hamza MS, Zhao Y. Curcuma wenyujin extract induces apoptosis and inhibits proliferation of human cervical cancer cells in vitro and in vivo. Integr Cancer Ther. 2010 Mar;9(1):36-49.

[35] Shan Dong Zhong Yi Xue Yuan Xue Bao (Journal of Shandong University School of Chinese Medicine), 1980; 1:30.

[36] Wu JY, Zhang QX, Leung PH. Inhibitory effects of ethyl acetate extract of Cordyceps sinensis mycelium on various cancer cells in culture and B16 melanoma in C57BL/6 mice. Phytomedicine. 2007 Jan;14(1):43-9.

[37] Yan LL, Zhang YJ, Gao WY, Man SL, Wang Y. In vitro and in vivo anticancer activity of steroid saponins of Paris polyphylla var. yunnanensis. School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China. Exp Oncol. 2009 Mar;31(1):27-32.

[38] Zhao Y, Kang LP, Liu YX, Liang YG, Tan DW, Yu ZY, Cong YW, Ma BP. Steroidal saponins from the rhizome of Paris polyphylla and their cytotoxic activities. Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing, PR China. Planta Med. 2009 Mar;75(4):356-63.

[39] Lee MS, Yuet-Wa JC, Kong SK, Yu B, Eng-Choon VO, Nai-Ching HW, Chung-Wai TM, Fung KP. Effects of polyphyllin D, a steroidal saponin in Paris polyphylla, in growth inhibition of human breast cancer cells and in xenograft. Department of Biochemistry, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China. Cancer Biol Ther. 2005 Nov;4(11):1248-54.

[40] Zhong Liu Yu Zhi Tong Xun (Journal of Prevention and Treatment of Cancer), 1976; 2:40.

[41] Zhong Cao Yao Xue (Study of Chinese Herbal Medicine), 1976; 15.

[42] Zhong Xi Yi Jie He Za Zhi (Journal of Integrated Chinese and Western Medicine), 1985; 2:115.

[43] Varinska L, Mirossay L, Mojzisova G, Mojzis J. Antiangogenic effect of selected phytochemicals. Pharmazie. 2010 Jan;65(1):57-63.

[44] Yance D.R., Sagar S.M. Targeting angiogenesis with integrative cancer therapies. Integr Cancer Ther. 2006, 5(1):9-29.